- 688,096 Americans are living with a brain tumor.
- 550,042 tumors are benign.
- 138,054 tumors are malignant.
- An estimated 68,470 people will receive primary brain tumor diagnoses this year.
- 45,300 will be benign.
- 23,180 will be malignant.
- Male: 55.2%
- Female: 44.8%
- The average survival rate for all malignant brain tumor patients is only 34.2%.
- Male: 32.6%
- Female: 44.8%
- For the most common form of primary malignant brain tumors, glioblastoma multiforme, the five-year relative survival rate is only approximately 5% - 10%, with most patients dying within 15 months.
- An estimated 13,770 people will die from malignant brain tumors (brain cancer) this year.
- The most prevalent brain tumor types in adults:
- Gliomas, such as glioblastoma multiforme, ependymomas, astrocytomas, and oligodendrogliomas
- An estimated 28,000 children in the U.S. are living with a brain tumor.
- An estimated 4,620 new cases of childhood and adolescent primary malignant and nonmalignant brain and CNS tumors are expected to be diagnosed in 2015.
- Pediatric brain tumors are the most prevalent form of childhood cancer in kids under 19.
- The average survival rate for all children with malignant brain tumors is 66%.
- Brain tumors are the leading cause of cancer-related deaths in children under 14, and the second leading cause of cancer-related deaths in children and young adults under 20.
- It is estimated that, in 2009, a total of 47,631.5 years of potential life were lost due to
- brain tumors in children 0-19 years old.
- The most prevalent brain tumor types in children:
- More than any other cancer, brain tumors can have lasting and life-altering physical, cognitive, and psychological impacts on a patient’s life.
- This means malignant brain tumors can often be described as equal parts neurological disease and deadly cancer.
- Even benign brain tumors can be deadly if they interfere with portions of the brain
responsible for vital bodily functions.
- There are more than 120 different types of brain tumors, many with their own multitude
- Despite the amount of brain tumors, and their devastating prognosis, there have only
been four (4) FDA approved drugs to treat brain tumors.
- For many tumor types, surgery and radiation remain the standard of care.
- There has never been a drug developed and approved specifically for pediatric brain tumors.
- The four approved therapies for brain tumors have provided only incremental improvements to patient survival, and mortality rates remain little changed over the past 30 years.
- Between 1998 and 2014, there were 78 investigational brain tumor drugs that entered
the clinical trial evaluation process. 75 failed, and only three (3) were approved (one
conditionally). That is a 25:1 failure ratio in developing new brain tumor treatments over
the past two decades.
- Brain tumors have the highest per-patient initial cost of care for any cancer group, with
an annualized mean net costs of care in 2010 US dollars at well over $100,000.
- In addition to primary brain tumors, each year in the United States and estimated
100,000 – 170,000 individual will be diagnosed with a secondary, or metastatic, brain
- Five to 25 percent of cancer patients will develop metastases in the brain.
- Many different cancer types often metastasize to the brain, including:
- Breast cancer
- Kidney cancer
- Lung cancer
- Melanoma (where nearly 50% of cases will metastasize to the brain)
Information provided by braintumor.org