Lanes will close on Route 110 near the Pentagon for up to two months as part of a state construction project.
The right lane of northbound Route 110 at Washington Blvd will close Wednesday night and the right lane of southbound Route 110 will close Thursday night at the same interchange.
The Virginia Department of Transportation said the closures are to remove and rebuild the bridge piers on the shoulders. Message signs alerting motorists to the lane closures are in place.
The left lane of northbound Route 110 and the left lane of southbound Route 110, which have been closed since early April to reconstruct the bridge pier in the median, will reopen Tuesday night.
The work is part of the Route 27 over Route 110 project, which is scheduled for completion next spring. The project will modify and repair the Washington Blvd bridge, including widening it and making it longer, wider and taller than the existing bridge.