INDIANAPOLIS — Earl Clark had 19 points and nine rebounds as top-seeded Louisville delivered one of the most crushing blowouts in regional round history — a 103-64 romp over Arizona on Friday.
Coach Rick Pitino and the Cardinals (31-5) topped 100 points for the first time this season, hit 14 3-pointers and nearly 57 percent from the field, moving into the Midwest final in impressive fashion.
Louisville will play Michigan State on Sunday for a trip to the Final Four.
Michigan State 67, Kansas 62
Goran Suton had 20 points and nine rebounds as Michigan State was steady from the foul line, rallying to defeat defending NCAA champion Kansas in the Midwest Regional semifinals.
Kalin Lucas added 18 points for the second-seeded Spartans (29-6).
Michigan State overcame a 13-point deficit in the first half and advanced to play Louisville on Sunday for a trip to the Final Four.
Sherron Collins scored 20 points and Cole Aldrich had 17 points and 14 rebounds for Kansas (27-7).
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Oklahoma 84, Syracuse 71
At Memphis, Tennessee, Blake Griffin bullied his way to 30 points and 14 rebounds, and Tony Crocker added a career-high 28 points as second-seeded Oklahoma beat Syracuse to reach its first regional final since 2003.
Oklahoma (30-5) will play top-seeded North Carolina in the South Regional final Sunday. The last time the Sooners made it this far, Syracuse beat them en route to their own national championship.
Flynn led Syracuse with 22 points despite playing the second half with a bruised back after that crunching collision with Griffin.
North Carolina 98, Gonzaga 77
Ty Lawson scored 17 of his 19 points in the first half as top-seeded North Carolina routed Gonzaga.
Tyler Hansbrough added 24 points and 10 rebounds for North Carolina, which won its 99th NCAA tournament game, breaking a tie with Kentucky for the most by any school.
Wayne Ellington scored 19 points and Danny Green added 13 for the Tar Heels (31-4), who reached the regional finals for the third straight year.
Jeremy Pargo led Gonzaga (28-6) with 16 points.