Reps for the couple confirmed to People that the Brazilian beauty is due this winter.
"Adriana and Marko are overjoyed that they are expecting their first child together and are excited to share the happy news and start their family together," their reps said.
Adriana and Marko were married on Valentine's Day this year. The couple eloped, opting for a small civil ceremony in Jackson Hole, Wyoming.
"We are so excited about our future together," the supermodel told People in February.
The couple reportedly met in 2006 and were engaged two years later. Marko proposed to Adriana on her 27th birthday.