Scarlett Johansson blew her nose last Wednesday. A week later a fan paid $5,300 for the tissue.
"I feel like it's valuable in some way ... I feel like I could sell it on eBay," she told Leno, who eagerly offered a box of tissues and encouraged her to blow.
"Should I really give a blow, though?" asked the actress.
"How much do you wanna help people in need? That's what it comes down to," replied the talk show host.
"So you're saying the more snot I produce...?" she asked.
Johansson then gave a hearty blow, leaving the tissue smeared with snot and lipstick.
She then autographed the tissue and announced she was putting up for auction with the proceeds to benefit USA Harvest, a group that picks up unsold food from restaurants and distributes it to the needy.